Baseline grids in newspaper design are the best way to achieve typographic consistency. There is nothing sloppier than seeing multiple columns of type with the lines out of alignment.
I can tell this is a popular topic because of all the videos I recently uploaded to YouTube, the one I did on working with grids made it to 100 views quicker than any other.
These two links, one to a previous post and one to the YouTube video should help you answer questions regarding the use of grids in page layout using InDesign. For any other questions, shoot me an e-mail, and I would be happy to respond.
The earlier post: http://newsdesignschool.com/newspaper-design-tip-baseline-grids/
The YouTube video: http://www.youtube.com/watch?v=2jEMjcWcGOM
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